BIOC6006 Classblog - 2010

Post comments and links relating to interesting genetic findings, announcements, papers and seminars to share them with your classmates. Your literature review abstracts will be posted here as well.

2.9.06

RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse


RNA RESPONSIBLE FOR HERITABLE CHANGES !!
BY: Rassoulzadegan, M. et al.
SOURCE: Nature 441, 469-474 (25 May 2006) .
NAME: PATEL NIRAV BHARATKUMAR.(41252361)

RNA can bring about heritable changes, this is something that is hard to believe is’nt it? But, based on the study carried out on mice it has been postulated that RNA can bring about heritable changes.
The study suggests that without the changes in the DNA structure there was a prominent change seen in the mice i.e. the white spots observed on the body. This is due to the fact that sperm and egg might trasmit the genetic information thorugh the RNA. The study involves paramutation : in this case, an allele interacts with its homologue and somehow causes in it a heritable epigenetic change.
Ok, wait for my review to learn and explore the facts!!!
Cheers,
NIRAV


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