BIOC6006 Classblog - 2010

Post comments and links relating to interesting genetic findings, announcements, papers and seminars to share them with your classmates. Your literature review abstracts will be posted here as well.

13.4.06

Homeotic gene repression homolog in humans

Hi,

After Tuesdays lecture Paul said to post here. So...

This one seemed interesting.

It concerns the protein hPCL3 (part of the PcG polycomb group of proteins). Which are
responsible for the 'stable epigenetic repression of homeotic genes'. The study has
found that the levels of the two proteins (large and small), which make up the complex,
are over expressed in many types of cancer. Including; colon, skin, lung, rectal,
cervical, uterus, and liver cancers.

Ok, now its in the right place. :)

Ashley.

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