To deacetylise or not to deacetylise?
Breast Cancer Research and Treatment (2005) 90: 15–2
this paper discusses acetylation and deacetylation of histones (in particular in H3). If you recall histone deacetylase (HDAC) is involved in deacetylation of histones and this study found the expression of HDAC proteins turns out to be a good indicator of cancer survival rates (in specific types of breast cancer). Whats really interesting is that based on previous findings, the authors were expecting quite the opposite result!
Padideh Zareh
this paper discusses acetylation and deacetylation of histones (in particular in H3). If you recall histone deacetylase (HDAC) is involved in deacetylation of histones and this study found the expression of HDAC proteins turns out to be a good indicator of cancer survival rates (in specific types of breast cancer). Whats really interesting is that based on previous findings, the authors were expecting quite the opposite result!
Padideh Zareh
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